Profhilo Injection in Malaysia: All You Need to Know

August 31, 2026

If your skin is becoming drier, less firm or less elastic despite following a good skincare routine, the concern may go beyond the skin surface. 


Profhilo is an injectable hyaluronic acid treatment designed to improve skin hydration, elasticity and overall skin quality while maintaining your natural facial features. 


For anyone considering a Profhilo injection in Malaysia, understanding how the treatment works, what it can improve, its possible side effects and how it differs from other injectable options can help you make a more informed decision. 


At RegenX Clinic, we offer Profhilo 64 and Profhilo Structura for different treatment needs. The appropriate option depends on your skin condition, facial ageing pattern and treatment goals. 


This guide explains what you need to know before deciding whether Profhilo is suitable for you. 


 


What Is Profhilo and How Does It Work? 


Profhilo is an injectable hyaluronic acid treatment designed to improve skin hydration, elasticity, firmness and overall skin quality. It contains high and low molecular weight hyaluronic acid, also known as HA. Hyaluronic acid occurs naturally in the body and helps retain moisture within the skin. 


As skin ages, changes in hyaluronic acid, collagen, elastic fibres and other supporting structures can contribute to dryness, fine lines, reduced firmness and skin laxity. 


Profhilo delivers hyaluronic acid directly into the treated tissue to improve hydration and support skin bio remodelling. Rather than simply filling individual lines, it works more broadly on the overall condition of the skin. 


According to the Malaysia Medical Device Authority registration for Profhilo, the Profhilo 3.2% formulation registered in Malaysia contains 32 mg of high molecular weight hyaluronic acid and 32 mg of low molecular weight hyaluronic acid in a 2 ml syringe. 


Clinical evidence also supports improvements in skin hydration, elasticity and mild skin laxity following Profhilo treatment. You can refer to the clinical evidence on Profhilo efficacy and safety for further details. 


 


Is Profhilo a Skin Booster? 


Yes, Profhilo is commonly categorised as a skin booster because it is an injectable treatment used to improve hydration and overall skin quality. However, it differs from many traditional skin boosters in its formulation and focus on skin bio remodelling. 




How Is Profhilo Different From Traditional Skin Boosters? 


Both Profhilo and traditional skin boosters can improve hydration and skin quality, but their treatment focus and injection approach can differ. 


Comparison Profhilo Traditional Skin Boosters
Main focus Hydration, elasticity, firmness and mild skin laxity Hydration, texture, smoothness and radiance
Approach Greater focus on skin bio remodelling Greater focus on improving overall skin condition
Injection method Commonly uses fewer strategic injection points Often uses multiple small injections across the treatment area


Profhilo may be considered when your concerns include dehydration together with reduced elasticity or mild skin laxity. 


The most suitable option still depends on your skin condition and the result you want to achieve. 


You can also explore the skin booster treatments available at RegenX Clinic. 


 


What Are the Main Profhilo Benefits? 


Profhilo Injection in Malaysia: All You Need to Know


Profhilo is mainly used to improve overall skin quality while maintaining a natural appearance. 


  • Improves skin hydration by helping the skin retain moisture and look fresher and more supple. 
  • Supports better skin elasticity as the skin begins to lose its natural bounce with age. 
  • Improves skin firmness and may help the skin feel smoother and more resilient. 
  • Helps with mild skin laxity by supporting overall skin quality and firmness. 
  • Softens the appearance of fine lines, especially those linked to dehydration and early skin ageing. 
  • Improves skin texture for a smoother and healthier looking complexion. 
  • Supports a fresher and more radiant appearance as hydration and overall skin quality improve. 
  • Maintains a natural look without significantly changing your facial features. 

 


Profhilo 64 vs Profhilo Structura: What Is the Difference? 


RegenX Clinic offers Profhilo 64 and Profhilo Structura, but the two should not be viewed as interchangeable treatments. 


They belong to the same Profhilo family but are designed with different treatment priorities. 


Comparison Profhilo 64 Profhilo Structura
Main focus Skin hydration and bio remodelling Deeper facial tissue support
Common concerns Dehydration, reduced elasticity, mild skin laxity and overall skin quality Age related changes involving deeper facial tissues
Treatment goal Improve the condition and quality of the skin Address deeper structural changes associated with facial ageing


Profhilo 64 is mainly considered when the treatment goal involves hydration, elasticity, firmness and overall skin quality. 


Profhilo Structura works with a different treatment focus. According to IBSA's information on Profhilo Structura, it was developed to target deeper facial tissues, particularly age related changes involving facial adipose tissue. 


Profhilo Structura is therefore not simply a stronger version of Profhilo 64. They address different aspects of facial ageing. 


A proper facial assessment helps determine whether your concern is mainly related to skin quality, deeper structural changes or both. 


 


Profhilo vs Rejuran vs PLINEST: Which Is Better? 


There is no single best treatment when comparing Profhilo vs Rejuran vs PLINEST. They contain different main ingredients and are selected for different treatment priorities. 



Profhilo is based on hyaluronic acid. Rejuran and PLINEST belong to the polynucleotide category and are commonly used as part of regenerative skin treatment approaches. 


Treatment Main Ingredient Main Focus May Be Considered For
Profhilo Hyaluronic acid Hydration and skin bio remodelling Dehydration, reduced elasticity, mild laxity and overall skin quality
Rejuran Healer Polynucleotides Skin repair and rejuvenation Texture, ageing skin and regenerative support
PLINEST Polynucleotides Skin bioregeneration Skin quality, texture, elasticity and regenerative support


The right choice depends on what your skin needs most. Profhilo may be more suitable when hydration, elasticity and mild laxity are the main concerns, while Rejuran or PLINEST may be considered when the focus is more on skin repair and regenerative support. 


A proper skin assessment can help determine which treatment is more suitable for your condition and goals. 


 


Who Is Suitable for Profhilo? 


Profhilo may be suitable for adults concerned about dehydrated or dull skin


Profhilo may be suitable for adults concerned about: 


  • Dehydrated or dull skin 
  • Fine lines 
  • Reduced elasticity 
  • Mild skin laxity 
  • Crepey texture 
  • Loss of firmness 

Suitability depends more on your skin condition and treatment goals than age alone. 


 


Who May Not Be Suitable for Profhilo? 


Profhilo may not be suitable for everyone. Treatment may need to be postponed or reconsidered if you have: 


  • Active infection or skin inflammation 
  • Certain medical conditions 
  • Pregnancy or breastfeeding 
  • Previous significant reactions to injectables 
  • Medication that may affect treatment safety or recovery 

A medical consultation is important to confirm whether Profhilo is suitable for you. 


 


What Happens During a Profhilo Treatment? 


A Profhilo treatment usually starts with a consultation. At RegenX Clinic, the doctor will assess your skin condition, concerns and treatment goals before deciding whether Profhilo is suitable. 


If Profhilo is recommended, the treatment process usually includes: 


1. Consultation and Assessment 


The doctor reviews your skin condition, medical history and treatment goals. 


2. Treatment Planning 


The suitable Profhilo option, treatment area and expected outcome are discussed. 


3. Skin Preparation 


The treatment area is cleaned and prepared before injection. 


4. Profhilo Injection 


Profhilo is injected at selected points according to the treatment area and individual plan. 


5. Aftercare Advice 


The doctor explains what to expect and how to care for the treated area after treatment. 


The exact process may vary depending on whether Profhilo 64 or Profhilo Structura is used and your individual treatment plan. 


 


How Many Profhilo Sessions Do You Need? 


A commonly used initial Profhilo 64 treatment approach involves two sessions approximately four weeks apart. However, your individual treatment plan may differ. 

The number and timing of sessions depend on factors such as: 


  • The Profhilo product being used 
  • Your skin condition 
  • Treatment area 
  • Treatment goals 
  • Individual response 

Maintenance treatment may be considered after the initial treatment course when appropriate. 


 


How Long Does Profhilo Last? 


Profhilo results typically last around 6 to 9 months, although the duration can vary from person to person. 


How long the results remain noticeable can depend on factors such as your age, baseline skin condition, metabolism, lifestyle, sun exposure and skincare habits. 


As the effects gradually reduce over time, maintenance treatment may be considered from around the six month mark depending on how your skin responds and your treatment goals. 


 


Profhilo Injection Treatment: Before and After 

 

Profhilo Injection Treatment: Before and After

What Are the Possible Profhilo Side Effects? 


Common Profhilo side effects are usually mild and temporary. These may include redness, swelling, tenderness, bruising and small bumps at the injection points. 


Most reactions settle within a few days. Contact your treating clinic if you experience worsening pain, unusual skin colour changes, increasing swelling or other unexpected symptoms. 


 


Is There Downtime After Profhilo? 


Profhilo generally involves minimal downtime, although temporary injection-related reactions may still occur. 


Small bumps, redness, swelling, tenderness or bruising may temporarily be visible. 


Some people may return to their usual activities quickly, while others may prefer to allow additional time for visible injection marks or swelling to settle. 


 


How Much Does Profhilo Cost in Malaysia? 


Profhilo treatment in Malaysia typically costs around RM2,000 to RM3,500 per session. The actual price depends on the clinic, amount of product used, treatment area and treatment plan. Profhilo Structura may also be priced differently from Profhilo 64. 


At RegenX Clinic, your doctor will first assess your skin and facial concerns before recommending the appropriate Profhilo option and treatment plan. 


 


How to Choose a Profhilo Clinic in Malaysia 


Before choosing where to receive Profhilo, look beyond promotional prices and before and after photographs. The overall clinical approach matters. 


1. Start With a Proper Skin and Facial Assessment 


Your skin and facial ageing pattern should be assessed before treatment is recommended. The clinic should be able to explain why Profhilo is appropriate and which Profhilo option matches your concern. 


2. Check the Product Being Used 


Ask what Profhilo product is being used and whether it is authentic. You should know what is being injected and why it has been selected for you. 


3. Understand What Results Are Realistic 


A proper consultation should explain both what Profhilo can improve and what it cannot. Be cautious with claims suggesting that a single injectable can solve every sign of skin or facial ageing. 


4. Consider Whether Another Treatment May Suit You Better 


Sometimes the most appropriate recommendation is not Profhilo. Depending on your skin condition, another skin booster treatment, Rejuran, PLINEST or another aesthetic treatment may be more appropriate. 


5. Consider Who Is Treating You 


RegenX Clinic is founded and led by Dr Dini, an LCP certified aesthetic physician with more than 15 years of medical experience. Treatment planning at RegenX focuses on assessing the concern first before recommending an injectable procedure. 


6. Consider Follow Up Care 


Treatment does not end once the injections are completed. An appropriate clinical setting should also be able to assess your recovery, answer concerns and manage unexpected reactions when necessary. 


 


Final Thoughts 


Profhilo is a skin bio remodelling treatment that may help improve hydration, elasticity, firmness and mild skin laxity while maintaining a natural appearance. 


For suitable patients, Profhilo 64 can be considered when the main concern is declining skin quality, while Profhilo Structura may be more relevant when deeper age-related facial changes are involved. 


However, Profhilo is not a one size fits all treatment. The most suitable option depends on your skin condition, facial ageing pattern and treatment goals. A proper assessment is therefore important before deciding whether Profhilo is the right treatment for you. 


 


Ready to Find Out If Profhilo Is Right for You? 


If you are considering Profhilo but are unsure whether Profhilo 64, Profhilo Structura or another skin rejuvenation treatment is more suitable, the best next step is a personalised consultation. 


At RegenX Clinic, our approach is doctor led. We first assess your skin condition, facial ageing pattern and treatment goals before recommending a treatment plan that matches your needs. 


Your treatment journey is guided by Dr Dini, an LCP certified aesthetic physician with more than 15 years of medical experience. She is also experienced in women’s wellness and anti-aging, making her well suited to support patients concerned about skin ageing, loss of firmness, reduced elasticity and overall skin quality. 


Through a personalised skin and facial assessment, we can better understand your concerns and recommend treatment which is more appropriate for you. 


Visit RegenX Clinic Putrajaya or RegenX Aesthetic Damansara Heights for a personalised consultation. 


Contact us on WhatsApp to learn more about Profhilo or book an appointment. 


 


Frequently Asked Questions About Profhilo 


1. What is Profhilo? 

Profhilo is an injectable hyaluronic acid treatment used to improve hydration, elasticity and overall skin quality. It contains high and low molecular weight hyaluronic acid and is commonly associated with skin bio remodelling. 


2. Is Profhilo a skin booster? 

Yes. Profhilo is commonly categorised as a skin booster. However, it differs from many traditional skin boosters because it places greater emphasis on hydration, elasticity, firmness and skin bio remodelling. 


3. What are the main Profhilo benefits? 

The main Profhilo benefits include improved hydration, elasticity, firmness, skin texture and mild skin laxity. The degree of improvement varies according to your skin condition and individual response. 


4. What is the difference between Profhilo 64 and Profhilo Structura? 

Profhilo 64 focuses mainly on hydration, elasticity and skin bio remodelling, while Profhilo Structura has a deeper treatment focus related to age related structural changes in facial tissues. 


They are different treatment options rather than stronger and weaker versions of the same treatment. 


5. What are the common Profhilo side effects? 

Common side effects may include temporary redness, swelling, tenderness, bruising and small bumps around the injection points. These reactions are usually temporary. 


6. How many Profhilo treatments do I need? 

Two sessions approximately four weeks apart are commonly used as an initial Profhilo 64 treatment approach. Your actual treatment schedule depends on the product selected, skin condition and treatment goals. 


7. When can I see Profhilo before and after results? 

Profhilo results usually develop gradually over the following weeks rather than immediately after injection. Hydration and overall skin quality may improve progressively as your skin responds to treatment. 


8. Is Profhilo better than Rejuran or PLINEST? 

No treatment is universally better. Profhilo is hyaluronic acid based and focuses strongly on hydration and skin bio remodelling, while Rejuran and PLINEST are polynucleotide-based treatments used more commonly for regenerative skin support. 


The better option depends on your skin condition and treatment goals. 


9. Where can I get Profhilo treatment in Malaysia? 

RegenX Clinic provides Profhilo treatment in Putrajaya and Damansara Heights, Kuala Lumpur. A consultation allows us to assess whether Profhilo 64, Profhilo Structura or another skin rejuvenation treatment is more suitable for your concerns. 


 


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